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RELPAX®( eletriptan) Has the use of RELPAX® been associated with rebound headache?

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Has the use of RELPAX® been associated with rebound headache?

Overuse of all triptans has been reported primarily in patients with chronic daily headache.1

The diagnostic criteria for triptan-overuse headache according to the International Headache Society (IHS), which can accessed at are as follows:

  • Headache present on ≥15 days/month, which developed or markedly worsened during medication overuse and which resolves or reverts to its previous pattern within 2 months after discontinuation of overused medication.2
  • Triptan intake (any formulation) on ≥10 days/month on a regular basis for > 3 months.2



  1. Relpax®(eletriptan hydrobromide) Product Information
  2. Headache Classification Committee of the International Headache Society (IHS). The International Classification of Headache Disorders, 3rd edition (beta version). Cephalalgia 2013; 33(9) 629–808.

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